Metabolic Enzymology

The online course offers a study of the functional and structural characteristics of metabolic pathway enzymes at the molecular level exploring fundamental protein chemistry that is relevant to understanding enzyme function within those pathways. Using molecular graphics software, students will examine high-resolution structures of enzymes and explore changes in structure that occur with classical enzyme mechanisms. Analysis of pre-steady state and steady-state enzymes activity, as well as enzyme inhibition, will be important aspects of the course.